2EZ9
Pyruvate oxidase variant F479W in complex with reaction intermediate analogue 2-phosphonolactyl-thiamin diphosphate
Summary for 2EZ9
Entry DOI | 10.2210/pdb2ez9/pdb |
Related | 1POW 1POX 1Y9D 2EZ4 2EZ8 2EZT 2EZU |
Descriptor | Pyruvate oxidase, MAGNESIUM ION, SODIUM ION, ... (6 entities in total) |
Functional Keywords | tpp enzyme, reaction intermediate analogue, oxidoreductase |
Biological source | Lactobacillus plantarum |
Total number of polymer chains | 2 |
Total formula weight | 135284.11 |
Authors | Wille, G.,Meyer, D.,Steinmetz, A.,Hinze, E.,Golbik, R.,Tittmann, K. (deposition date: 2005-11-10, release date: 2006-04-25, Last modification date: 2023-08-23) |
Primary citation | Wille, G.,Meyer, D.,Steinmetz, A.,Hinze, E.,Golbik, R.,Tittmann, K. The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography. Nat.Chem.Biol., 2:324-328, 2006 Cited by PubMed: 16680160DOI: 10.1038/nchembio788 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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