2EOT
SOLUTION STRUCTURE OF EOTAXIN, AN ENSEMBLE OF 32 NMR SOLUTION STRUCTURES
Summary for 2EOT
| Entry DOI | 10.2210/pdb2eot/pdb |
| Descriptor | EOTAXIN (1 entity in total) |
| Functional Keywords | cytokine, chemokine, protein synthesis, eotaxin, solution structure, ccr3, eosinophil |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: P51671 |
| Total number of polymer chains | 1 |
| Total formula weight | 8380.94 |
| Authors | Crump, M.P.,Rajarathnam, K.,Kim, K.-S.,Clark-Lewis, I.,Sykes, B.D. (deposition date: 1998-06-29, release date: 1998-11-11, Last modification date: 2024-11-06) |
| Primary citation | Crump, M.P.,Rajarathnam, K.,Kim, K.S.,Clark-Lewis, I.,Sykes, B.D. Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation. J.Biol.Chem., 273:22471-22479, 1998 Cited by PubMed Abstract: The solution structure of the CCR3-specific chemokine, eotaxin, has been determined by NMR spectroscopy. The quaternary structure of eotaxin was investigated by ultracentrifugation and NMR, and it was found to be in equilibrium between monomer and dimer under a wide range of conditions. At pH PubMed: 9712872 DOI: 10.1074/jbc.273.35.22471 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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