2EOT

SOLUTION STRUCTURE OF EOTAXIN, AN ENSEMBLE OF 32 NMR SOLUTION STRUCTURES

2EOT の概要

• エントリーDOI: 10.2210/pdb2eot/pdb
• 分子名称: EOTAXIN (1 entity in total)
• 機能のキーワード: cytokine, chemokine, protein synthesis, eotaxin, solution structure, ccr3, eosinophil
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P51671
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 8380.94

構造登録者

Crump, M.P.,Rajarathnam, K.,Kim, K.-S.,Clark-Lewis, I.,Sykes, B.D. (登録日: 1998-06-29, 公開日: 1998-11-11, 最終更新日: 2024-11-06)

主引用文献

Crump, M.P.,Rajarathnam, K.,Kim, K.S.,Clark-Lewis, I.,Sykes, B.D.
Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
J.Biol.Chem., 273:22471-22479, 1998

PubMed Abstract: The solution structure of the CCR3-specific chemokine, eotaxin, has been determined by NMR spectroscopy. The quaternary structure of eotaxin was investigated by ultracentrifugation and NMR, and it was found to be in equilibrium between monomer and dimer under a wide range of conditions. At pH PubMed: 9712872
DOI: 10.1074/jbc.273.35.22471

実験手法

SOLUTION NMR