2EA3

Crystal Structure Of Cellulomonas Bogoriensis Chymotrypsin

2EA3 の概要

• エントリーDOI: 10.2210/pdb2ea3/pdb
• 分子名称: Chymotrypsin, SULFATE ION (3 entities in total)
• 機能のキーワード: celloulomonas, chymotrypsin, protease, hydrolase
• 由来する生物種: Cellulomonas bogoriensis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19078.85

構造登録者

Shaw, A.,Bott, R. (登録日: 2007-01-30, 公開日: 2007-04-24, 最終更新日: 2024-11-06)

主引用文献

Shaw, A.,Saldajeno, M.L.,Kolkman, M.A.,Jones, B.E.,Bott, R.
Structure determination and analysis of a bacterial chymotrypsin from Cellulomonas bogoriensis
Acta Crystallogr.,Sect.F, 63:266-269, 2007

PubMed Abstract: The crystal structure of a secreted chymotrypsin from the alkaliphile Cellulomonas bogoriensis has been determined using data to 1.78 A resolution and refined to a crystallographic R factor of 0.167. The crystal structure reveals a large P1 substrate-specificity pocket, as expected for chymotrypsins. The structure is compared with close structural homologues. This comparison does not reveal clear reasons for the alkali tolerance of the enzyme, but the greater compactness of the structure and lowered hydrogen bonding may play a role.

PubMed: 17401191
DOI: 10.1107/S1744309107008937

実験手法

X-RAY DIFFRACTION (1.78 Å)