2E3W

X-ray structure of native RNase A

Summary for 2E3W

Entry DOI	10.2210/pdb2e3w/pdb
Related	2NUI
Descriptor	Ribonuclease pancreatic, CHLORIDE ION (3 entities in total)
Functional Keywords	alpha-helix, beta-sheet, hydrolase
Biological source	Bos taurus (cattle)
Cellular location	Secreted: P61823
Total number of polymer chains	1
Total formula weight	13814.68
Authors	Boerema, D.J.,Tereshko, V.A.,Kent, S.B.H. (deposition date: 2006-11-30, release date: 2007-10-30, Last modification date: 2024-10-09)
Primary citation	Boerema, D.J.,Tereshko, V.A.,Kent, S.B. Total synthesis by modern chemical ligation methods and high resolution (1.1 A) X-ray structure of ribonuclease A Biopolymers, 90:278-286, 2008 Cited by PubMed Abstract: The total chemical synthesis of RNase A using modern chemical ligation methods is described, illustrating the significant advances that have been made in chemical protein synthesis since Gutte and Merrifield's pioneering preparation of RNase A in 1969. The identity of the synthetic product was confirmed through rigorous characterization, including the determination of the X-ray crystal structure to 1.1 Angstrom resolution. PubMed: 17610259 DOI: 10.1002/bip.20800 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.05 Å)

Structure validation