2DX1
Crystal structure of RhoGEF protein Asef
Summary for 2DX1
Entry DOI | 10.2210/pdb2dx1/pdb |
Descriptor | Rho guanine nucleotide exchange factor 4 (2 entities in total) |
Functional Keywords | rho-gef, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 3: Cytoplasm: Q9NR80 |
Total number of polymer chains | 1 |
Total formula weight | 55623.78 |
Authors | Murayama, K.,Kato-Murayama, M.,Terada, T.,Shirouzu, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2006-08-22, release date: 2007-01-02, Last modification date: 2011-07-13) |
Primary citation | Murayama, K.,Shirouzu, M.,Kawasaki, Y.,Kato-Murayama, M.,Hanawa-Suetsugu, K.,Sakamoto, A.,Katsura, Y.,Suenaga, A.,Toyama, M.,Terada, T.,Taiji, M.,Akiyama, T.,Yokoyama, S. Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism J.Biol.Chem., 282:4238-4242, 2007 Cited by PubMed: 17190834DOI: 10.1074/jbc.C600234200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.36 Å) |
Structure validation
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