2DSY

Crystal structure of TTHA0281 from thermus thermophilus HB8

2DSY の概要

• エントリーDOI: 10.2210/pdb2dsy/pdb
• 分子名称: Hypothetical protein TTHA0281, MAGNESIUM ION, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: structural genomics, thermus thermophilus hb8, hypothetical protein, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, unknown function
• 由来する生物種: Thermus thermophilus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 39741.31

構造登録者

Okazaki, N.,Kumei, M.,Shinkai, A.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2006-07-07, 公開日: 2007-03-27, 最終更新日: 2024-11-06)

主引用文献

Okazaki, N.,Kumei, M.,Manzoku, M.,Kuramitsu, S.,Shirouzu, M.,Shinkai, A.,Yokoyama, S.
Structure of a UPF0150-family protein from Thermus thermophilus HB8
ACTA CRYSTALLOGR.,SECT.F, 63:173-177, 2007

PubMed Abstract: TTHA0281 is a hypothetical protein from Thermus thermophilus HB8 that belongs to an uncharacterized protein family, UPF0150, in the Pfam database and to COG1598 in the National Center for Biotechnology Information Database of Clusters of Orthologous Groups. The X-ray crystal structure of the protein was determined by a multiple-wavelength anomalous dispersion technique and was refined at 1.9 A resolution to a final R factor of 18.5%. The TTHA0281 monomer adopts an alpha-beta-beta-beta-alpha fold and forms a homotetramer. Based on the properties and functions of structural homologues of the TTHA0281 monomer, the TTHA0281 protein is speculated to be involved in RNA metabolism, including RNA binding and cleavage.

PubMed: 17329807
DOI: 10.1107/S1744309107006070

実験手法

X-RAY DIFFRACTION (1.9 Å)