2DQY

Crystal structure of human carboxylesterase in complex with cholate and palmitate

Summary for 2DQY

Entry DOI	10.2210/pdb2dqy/pdb
Related	2DQZ 2DR0 2H7C
Descriptor	Liver carboxylesterase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, ... (7 entities in total)
Functional Keywords	cholesterol metabolism, foam cells, macrophage, monocyte, atherosclerosis, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	183525.38
Authors	Bencharit, S.,Edwards, C.C.,Morton, C.L.,Howard-Williams, E.L.,Potter, P.M.,Redinbo, M.R. (deposition date: 2006-06-02, release date: 2006-08-29, Last modification date: 2023-10-25)
Primary citation	Bencharit, S.,Edwards, C.C.,Morton, C.L.,Howard-Williams, E.L.,Kuhn, P.,Potter, P.M.,Redinbo, M.R. Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1 J.Mol.Biol., 363:201-214, 2006 Cited by PubMed: 16962139 DOI: 10.1016/j.jmb.2006.08.025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation