2DQY
Crystal structure of human carboxylesterase in complex with cholate and palmitate
Summary for 2DQY
Entry DOI | 10.2210/pdb2dqy/pdb |
Related | 2DQZ 2DR0 2H7C |
Descriptor | Liver carboxylesterase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, ... (7 entities in total) |
Functional Keywords | cholesterol metabolism, foam cells, macrophage, monocyte, atherosclerosis, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 183525.38 |
Authors | Bencharit, S.,Edwards, C.C.,Morton, C.L.,Howard-Williams, E.L.,Potter, P.M.,Redinbo, M.R. (deposition date: 2006-06-02, release date: 2006-08-29, Last modification date: 2023-10-25) |
Primary citation | Bencharit, S.,Edwards, C.C.,Morton, C.L.,Howard-Williams, E.L.,Kuhn, P.,Potter, P.M.,Redinbo, M.R. Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1 J.Mol.Biol., 363:201-214, 2006 Cited by PubMed: 16962139DOI: 10.1016/j.jmb.2006.08.025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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