2DDQ

Crystal Structure of the Fab fragment of a R310 antibody complexed with (R)-HNE-histidine adduct

Summary for 2DDQ

• Entry DOI: 10.2210/pdb2ddq/pdb
• Descriptor: R310 antibody heavy chain, R310 antibody light chain, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
• Functional Keywords: monoclonal antibody, 4-hydroxy-2-nonenal, immunoglobulin, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 47406.94

Authors

Ito, S. (deposition date: 2006-02-02, release date: 2006-07-11, Last modification date: 2011-07-13)

• Primary citation: Akagawa, M.,Ito, S.,Toyoda, K.,Ishii, Y.,Tatsuda, E.,Shibata, T.,Yamaguchi, S.,Kawai, Y.,Ishino, K.,Kishi, Y.,Adachi, T.,Tsubata, T.,Takasaki, Y.,Hattori, N.,Matsuda, T.,Uchida, K.; Bispecific abs against modified protein and DNA with oxidized lipids; Proc.Natl.Acad.Sci.Usa, 103:6160-6165, 2006; PubMed: 16603628; DOI: 10.1073/pnas.0600865103

Experimental method

X-RAY DIFFRACTION (2.35 Å)