2DDQ

Crystal Structure of the Fab fragment of a R310 antibody complexed with (R)-HNE-histidine adduct

2DDQ の概要

• エントリーDOI: 10.2210/pdb2ddq/pdb
• 分子名称: R310 antibody heavy chain, R310 antibody light chain, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
• 機能のキーワード: monoclonal antibody, 4-hydroxy-2-nonenal, immunoglobulin, immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47406.94

構造登録者

Ito, S. (登録日: 2006-02-02, 公開日: 2006-07-11, 最終更新日: 2011-07-13)

• 主引用文献: Akagawa, M.,Ito, S.,Toyoda, K.,Ishii, Y.,Tatsuda, E.,Shibata, T.,Yamaguchi, S.,Kawai, Y.,Ishino, K.,Kishi, Y.,Adachi, T.,Tsubata, T.,Takasaki, Y.,Hattori, N.,Matsuda, T.,Uchida, K.; Bispecific abs against modified protein and DNA with oxidized lipids; Proc.Natl.Acad.Sci.Usa, 103:6160-6165, 2006; PubMed: 16603628; DOI: 10.1073/pnas.0600865103

実験手法

X-RAY DIFFRACTION (2.35 Å)