2CNA

THE COVALENT AND THREE-DIMENSIONAL STRUCTURE OF CONCANAVALIN A, IV.ATOMIC COORDINATES,HYDROGEN BONDING,AND QUATERNARY STRUCTURE

2CNA の概要

• エントリーDOI: 10.2210/pdb2cna/pdb
• 分子名称: CONCANAVALIN A, MANGANESE (II) ION, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: lectin (agglutinin)
• 由来する生物種: Canavalia ensiformis (jack bean)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25691.31

構造登録者

Reekejunior, G.N.,Becker, J.W.,Edelman, G.M. (登録日: 1975-04-01, 公開日: 1977-03-16, 最終更新日: 2024-02-14)

主引用文献

Reeke Jr., G.N.,Becker, J.W.,Edelman, G.M.
The covalent and three-dimensional structure of concanavalin A. IV. Atomic coordinates, hydrogen bonding, and quaternary structure.
J.Biol.Chem., 250:1525-1547, 1975

PubMed Abstract: The coordinates of the individual non-hydrogen atoms of the lectin concanavalin A have been determined from the molecular model at 2.0-A resolution and have been adjusted to make them consistent with the known stereochemistry of the constituent amino acid residues. From the coordinates, an analysis has been made of all intra- and intersubunit interactions in the molecule, yielding a description of the hydrogen-bonded structure of the monomer, including two extensive pleated sheet structures and other features of the folding of the polypeptide chain. The description of the noncovalent bonding is extended to include the interactions involved in stabilization of the dimeric and tetrameric structures of the molecule. The complete description of the molecular structure provides a basis for analysis of the biological activities of concanavalin A.

PubMed: 1112816

実験手法

X-RAY DIFFRACTION (2 Å)