2CL3

Crystal structure of human Cleavage and Polyadenylation Specificity Factor 5 (CPSF5)

Summary for 2CL3

Entry DOI	10.2210/pdb2cl3/pdb
Descriptor	CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5 (2 entities in total)
Functional Keywords	precursor mrna cleavage factor im, mrna, cpsf5, cfim25, rna-binding, nuclear protein, mrna processing, phosphorylation
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus: O43809
Total number of polymer chains	1
Total formula weight	26720.65
Authors	Stenmark, P.,Hogbom, M.,Arrowsmith, C.,Berglund, H.,Collins, R.,Edwards, A.,Ehn, M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Kotenyova, T.,Magnusdottir, A.,Nilsson-Ehle, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Thorsell, A.G.,Van Den Berg, S.,Wallden, K.,Weigelt, J.,Nordlund, P. (deposition date: 2006-04-25, release date: 2006-05-04, Last modification date: 2024-05-08)
Primary citation	Tresaugues, L.,Stenmark, P.,Schuler, H.,Flodin, S.,Welin, M.,Nyman, T.,Hammarstrom, M.,Moche, M.,Graslund, S.,Nordlund, P. The Crystal Structure of Human Cleavage and Polyadenylation Specific Factor-5 Reveals a Dimeric Nudix Protein with a Conserved Catalytic Site. Proteins, 73:1047-, 2008 Cited by PubMed: 18767156 DOI: 10.1002/PROT.22198 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation