2CL3

Crystal structure of human Cleavage and Polyadenylation Specificity Factor 5 (CPSF5)

2CL3 の概要

• エントリーDOI: 10.2210/pdb2cl3/pdb
• 分子名称: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5 (2 entities in total)
• 機能のキーワード: precursor mrna cleavage factor im, mrna, cpsf5, cfim25, rna-binding, nuclear protein, mrna processing, phosphorylation
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Nucleus: O43809
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26720.65

構造登録者

Stenmark, P.,Hogbom, M.,Arrowsmith, C.,Berglund, H.,Collins, R.,Edwards, A.,Ehn, M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Kotenyova, T.,Magnusdottir, A.,Nilsson-Ehle, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Thorsell, A.G.,Van Den Berg, S.,Wallden, K.,Weigelt, J.,Nordlund, P. (登録日: 2006-04-25, 公開日: 2006-05-04, 最終更新日: 2024-05-08)

• 主引用文献: Tresaugues, L.,Stenmark, P.,Schuler, H.,Flodin, S.,Welin, M.,Nyman, T.,Hammarstrom, M.,Moche, M.,Graslund, S.,Nordlund, P.; The Crystal Structure of Human Cleavage and Polyadenylation Specific Factor-5 Reveals a Dimeric Nudix Protein with a Conserved Catalytic Site.; Proteins, 73:1047-, 2008; PubMed: 18767156; DOI: 10.1002/PROT.22198

実験手法

X-RAY DIFFRACTION (1.9 Å)