2C9D

Lumazine Synthase from Mycobacterium tuberculosis Bound to 3-(1,3,7- TRIHYDRO-9-D-RIBITYL-2,6,8-PURINETRIONE-7-YL)HEXANE 1-PHOSPHATE

2C9D の概要

• エントリーDOI: 10.2210/pdb2c9d/pdb
• 関連するPDBエントリー: 1W19 1W29 2C92 2C94 2C97 2C9B
• 分子名称: 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE, 3-(1,3,7-TRIHYDRO-9-D-RIBITYL-2,6,8-PURINETRIONE-7-YL ) HEXANE 1-PHOSPHATE, POTASSIUM ION, ... (5 entities in total)
• 機能のキーワード: transferase, riboflavin biosynthesis, mycobacterium tuberculosis, lumazine synthase, inhibitor binding
• 由来する生物種: MYCOBACTERIUM TUBERCULOSIS
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 169600.40

構造登録者

Morgunova, E.,Illarionov, B.,Jin, G.,Haase, I.,Fischer, M.,Cushman, M.,Bacher, A.,Ladenstein, R. (登録日: 2005-12-09, 公開日: 2006-12-13, 最終更新日: 2023-12-13)

• 主引用文献: Morgunova, E.,Illarionov, B.,Sambaiah, T.,Haase, I.,Bacher, A.,Cushman, M.,Fischer, M.,Ladenstein, R.; Structural and Thermodynamic Insights Into the Binding Mode of Five Novel Inhibitors of Lumazine Synthase from Mycobacterium Tuberculosis.; FEBS J., 273:4790-4804, 2006; PubMed: 16984393; DOI: 10.1111/J.1742-4658.2006.05481.X

実験手法

X-RAY DIFFRACTION (2.8 Å)