2C6N

Structure of human somatic angiontensin-I converting enzyme N domain with lisinopril

2C6N の概要

• エントリーDOI: 10.2210/pdb2c6n/pdb
• 関連するPDBエントリー: 2C6F
• 関連するBIRD辞書のPRD_ID: PRD_000560
• 分子名称: ANGIOTENSIN-CONVERTING ENZYME, SOMATIC ISOFORM, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: hydrolase, angiotensin-i converting enzyme, n domain, zinc metallopeptidase, metalloprotease, angiotensin, lisinopril, carboxypeptidase, glycoprotein, metal-binding, phosphorylation, protease, transmembrane, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 144061.86

構造登録者

Corradi, H.R.,Schwager, S.L.U.,Nichinda, A.,Sturrock, E.D.,Acharya, K.R. (登録日: 2005-11-10, 公開日: 2006-03-15, 最終更新日: 2023-12-13)

• 主引用文献: Corradi, H.R.,Schwager, S.L.,Nchinda, A.T.,Sturrock, E.D.,Acharya, K.R.; Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design.; J. Mol. Biol., 357:964-974, 2006; PubMed: 16476442; DOI: 10.1016/j.jmb.2006.01.048

実験手法

X-RAY DIFFRACTION (3 Å)