2C5R

The structure of phage phi29 replication organizer protein p16.7 in complex with double stranded DNA

2C5R の概要

• エントリーDOI: 10.2210/pdb2c5r/pdb
• 関連するPDBエントリー: 1ZAE 2BNK
• 分子名称: EARLY PROTEIN P16.7, 5'-D(*TP*CP*CP*AP*CP*CP*GP*GP)-3', 5'-D(*CP*CP*GP*GP*TP*GP*GP*AP)-3', ... (4 entities in total)
• 機能のキーワード: dna-binding protein-dna complex, dna-binding protein, complex (dna-binding protein-dna), dna-binding protein/dna
• 由来する生物種: BACILLUS PHAGE PHI29
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 52483.03

構造登録者

Albert, A.,Jimenez, M.,Munoz-Espin, D.,Asensio, J.L.,Hermoso, J.A.,Salas, M.,Meijer, W.J.J. (登録日: 2005-10-31, 公開日: 2005-11-08, 最終更新日: 2023-12-13)

主引用文献

Albert, A.,Munoz-Espin, D.,Jimenez, M.,Asensio, J.L.,Hermoso, J.A.,Salas, M.,Meijer, W.J.J.
Structural Basis for Membrane Anchorage of Viral Phi 29 DNA During Replication.
J.Biol.Chem., 280:42486-, 2005

PubMed Abstract: Prokaryotic DNA replication is compartmentalized at the cellular membrane. Functional and biochemical studies showed that the Bacillus subtilis phage 29-encoded membrane protein p16.7 is directly involved in the organization of membrane-associated viral DNA replication. The structure of the functional domain of p16.7 in complex with DNA, presented here, reveals the multimerization mode of the protein and provides insights in the organization of the phage genome at the membrane of the infected cell.

PubMed: 16275651
DOI: 10.1074/JBC.C500429200

実験手法

X-RAY DIFFRACTION (2.9 Å)