2C27

The Structure of Mycothiol Synthase in Complex with des- AcetylMycothiol and CoenzymeA.

Summary for 2C27

• Entry DOI: 10.2210/pdb2c27/pdb
• Related: 1OZP 1P0H
• Descriptor: MYCOTHIOL SYNTHASE, (1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside, ACETYL COENZYME *A, ... (5 entities in total)
• Functional Keywords: synthase, mycobacterium tuberculosis, mycothiol synthase, des- acetylmycothiol, acetyltransferase, gnat, gcn5 related n- acetyltransferase
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Total number of polymer chains: 1
• Total formula weight: 35660.60

Authors

Vetting, M.W.,Yu, M.,Rendle, P.M.,Blanchard, J.S. (deposition date: 2005-09-26, release date: 2005-12-01, Last modification date: 2023-12-13)

• Primary citation: Vetting, M.W.,Yu, M.,Rendle, P.M.,Blanchard, J.S.; The Substrate-Induced Conformational Change of Mycobacterium Tuberculosis Mycothiol Synthase.; J.Biol.Chem., 281:2795-2802, 2006; PubMed: 16326705; DOI: 10.1074/JBC.M510798200

Experimental method

X-RAY DIFFRACTION (1.8 Å)