2BPN

SOLUTION STRUCTURE OF DESULFOVIBRIO VULGARIS (HILDENBOROUGH) FERRICYTOCHROME C3, NMR, 20 STRUCTURES

2BPN の概要

• エントリーDOI: 10.2210/pdb2bpn/pdb
• 関連するPDBエントリー: 1A2I 1GX7 1MDV 2CTH 2CYM
• NMR情報: BMRB: 5625
• 分子名称: CYTOCHROME C3, HEME C (2 entities in total)
• 機能のキーワード: electron transport, hemeprotein, cytochrome c3, redox cooperativity, redox-bohr cooperativity, transduction, paramagnetic
• 由来する生物種: DESULFOVIBRIO VULGARIS
• 細胞内の位置: Periplasm: P00131
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14161.48

構造登録者

Messias, A.C.,Aguiar, A.P.,Brennan, L.,Xavier, A.V.,Turner, D.L. (登録日: 2005-04-21, 公開日: 2006-03-15, 最終更新日: 2024-10-09)

主引用文献

Messias, A.C.,Aguiar, A.P.,Brennan, L.,Salgueiro, C.A.,Saraiva, L.M.,Xavier, A.V.,Turner, D.L.
Solution Structures of Tetrahaem Ferricytochrome C(3) from Desulfovibrio Vulgaris (Hildenborough) and its K45Q Mutant: The Molecular Basis of Cooperativity.
Biochim.Biophys.Acta, 1757:143-, 2006

PubMed Abstract: The NMR structure of the oxidised wild-type cytochrome c3 from Desulfovibrio vulgaris Hildenborough was determined in solution. Using a newly developed methodology, NMR data from the K45Q mutant was then grafted onto data from the wild-type protein to determine the structure in the region of the mutation. The structural origins of the redox-Bohr effect and haem-haem cooperativities are discussed with respect to the redox-related conformational changes observed in solution.

PubMed: 16527248
DOI: 10.1016/J.BBABIO.2006.01.007

実験手法

SOLUTION NMR