2BK3

Human Monoamine Oxidase B in complex with Farnesol

2BK3 の概要

• エントリーDOI: 10.2210/pdb2bk3/pdb
• 関連するPDBエントリー: 1GOS 1H8R 1OJ9 1OJA 1OJB 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK4 2BK5
• 分子名称: AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, ... (4 entities in total)
• 機能のキーワード: acetylation, farnesol, fad, fad-containing amine oxidase, flavoprotein, maob, mitochondrion, oxidoreductase, transmembrane
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 119691.29

構造登録者

Binda, C.,Edmondson, D.E.,Mattevi, A. (登録日: 2005-02-10, 公開日: 2005-02-14, 最終更新日: 2023-12-13)

• 主引用文献: Hubalek, F.,Binda, C.,Khalil, A.,Li, M.,Mattevi, A.,Castagnoli, N.,Edmondson, D.E.; Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors.; J. Biol. Chem., 280:15761-15766, 2005; PubMed: 15710600; DOI: 10.1074/jbc.M500949200

実験手法

X-RAY DIFFRACTION (1.8 Å)