2BJ2

RNA LOOP-LOOP COMPLEX: THE COLE1 INVERTED LOOP SEQUENCE, NMR, MINIMIZED AVERAGE STRUCTURE

Summary for 2BJ2

• Entry DOI: 10.2210/pdb2bj2/pdb
• Related: 1BJ2
• Descriptor: RNA (5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*AP*UP*GP*GP*UP*UP*CP*GP*UP*UP*GP*CP*C)-3'), RNA (5'-R(*GP*CP*AP*CP*CP*GP*AP*AP*CP*CP*AP*UP*CP*CP*GP*GP*UP*GP*C)-3') (2 entities in total)
• Functional Keywords: cole1 rna, loop-loop complex, kiss complex, ribonucleic acid, rna
• Total number of polymer chains: 2
• Total formula weight: 12812.72

Authors

Lee, A.J.,Crothers, D.M. (deposition date: 1998-07-02, release date: 1999-02-02, Last modification date: 2024-05-22)

Primary citation

Lee, A.J.,Crothers, D.M.
The solution structure of an RNA loop-loop complex: the ColE1 inverted loop sequence.
Structure, 6:993-1005, 1998

PubMed Abstract: Replication of the ColE1 plasmid of Escherichia coli is regulated by the interaction of sense and antisense plasmid-encoded transcripts. The antisense RNA I negatively regulates the replication of the plasmid by duplex formation with complementary RNA II. The interaction is initiated by the formation of a double helix between seven-nucleotide loops from each RNA and is stabilized by binding of the RNA one modulator (ROM) protein. The ROM protein is thought to recognize a specific RNA structure, regardless of sequence.

PubMed: 9739090
DOI: 10.1016/S0969-2126(98)00101-4

Experimental method

SOLUTION NMR