2BE0

Complex Between Paromomycin Derivative JS5-39 and the 16S-Rrna A-Site.

2BE0 の概要

関連するPDBエントリー1J7T 2BEE 2ESI 2ESJ
関連するBIRD辞書のPRD_IDPRD_000042
分子名称5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', (2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3R,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R,4R,5S,6R)-3-AMINO-4,5-DIHYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-2-(HYDROXYMETHYL)-4-(2-((R)-PIPERIDIN-3-YLMETHYLAMINO)ETHOXY)-TETRAHYDROFURAN-3-YLOXY)-TETRAHYDRO-2H-PYRAN-3,4-DIOL (3 entities in total)
機能のキーワードrna-aminoglycoside interactions, a site, uou pairs, aa bulges, rna-antibiotic complex, rna/antibiotic
由来する生物種Streptomyces rimosus subsp. paromomycinus
ポリマー鎖数2
分子量合計15608.23
構造登録者
Francois, B.,Westhof, E. (登録日: 2005-10-21, 公開日: 2005-12-20, 最終更新日: 2011-07-13)
主引用文献
Francois, B.,Szychowski, J.,Adhikari, S.S.,Pachamuthu, K.,Swayze, E.E.,Griffey, R.H.,Migawa, M.T.,Westhof, E.,Hanessian, S.
Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site
ANGEW.CHEM.INT.ED.ENGL., 43:6735-6738, 2004
PubMed: 15593140 (主引用文献が同じPDBエントリー)
DOI: 10.1002/anie.200462092
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.63 Å)
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構造検証レポート

ClashscoreRSRZ outliersRNA backbone1000.69MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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