2B1A

Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG1033 peptide

Summary for 2B1A

• Entry DOI: 10.2210/pdb2b1a/pdb
• Related: 2B0S 2B1H
• Descriptor: Fab 2219, light chain, Fab 2219, heavy chain, UG1033 peptide of Exterior membrane glycoprotein GP120, ... (4 entities in total)
• Functional Keywords: fab-peptide complex; hiv-1; gp120; v3 loop, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 49567.78

Authors

Stanfield, R.L.,Gorny, M.K.,Zolla-Pazner, S.,Wilson, I.A. (deposition date: 2005-09-15, release date: 2006-07-04, Last modification date: 2023-08-23)

• Primary citation: Stanfield, R.L.,Gorny, M.K.,Zolla-Pazner, S.,Wilson, I.A.; Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.; J.Virol., 80:6093-6105, 2006; PubMed: 16731948; DOI: 10.1128/JVI.00205-06

Experimental method

X-RAY DIFFRACTION (2.348 Å)