2AXF
The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation
Summary for 2AXF
Entry DOI | 10.2210/pdb2axf/pdb |
Related | 2AXG |
Descriptor | HLA class I histocompatibility antigen, B*3508 heavy chain, Beta-2-microglobulin, 10-mer peptide from BZLF1 trans-activator protein, ... (5 entities in total) |
Functional Keywords | immune response, pmhc, immune system-gene regulation complex, immune system/gene regulation |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P30685 Secreted . Note=(Microbial infection) In the presence of M: P61769 Host nucleus : P03206 |
Total number of polymer chains | 3 |
Total formula weight | 44909.66 |
Authors | Tynan, F.E.,Elhassen, D.,Purcell, A.W.,Burrows, J.M.,Borg, N.A.,Miles, J.J.,Williamson, N.A.,Green, K.J.,Tellam, J.,Kjer-Nielsen, L.,McCluskey, J.,Rossjohn, J.,Burrows, S.R. (deposition date: 2005-09-05, release date: 2005-11-29, Last modification date: 2017-10-11) |
Primary citation | Tynan, F.E.,Elhassen, D.,Purcell, A.W.,Burrows, J.M.,Borg, N.A.,Miles, J.J.,Williamson, N.A.,Green, K.J.,Tellam, J.,Kjer-Nielsen, L.,McCluskey, J.,Rossjohn, J.,Burrows, S.R. The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation J.Exp.Med., 202:1249-1260, 2005 Cited by PubMed: 16275762DOI: 10.1084/jem.20050864 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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