2AXF

The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation

2AXF の概要

• エントリーDOI: 10.2210/pdb2axf/pdb
• 関連するPDBエントリー: 2AXG
• 分子名称: HLA class I histocompatibility antigen, B*3508 heavy chain, Beta-2-microglobulin, 10-mer peptide from BZLF1 trans-activator protein, ... (5 entities in total)
• 機能のキーワード: immune response, pmhc, immune system-gene regulation complex, immune system/gene regulation
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P30685; Secreted . Note=(Microbial infection) In the presence of M: P61769; Host nucleus : P03206
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44909.66

構造登録者

Tynan, F.E.,Elhassen, D.,Purcell, A.W.,Burrows, J.M.,Borg, N.A.,Miles, J.J.,Williamson, N.A.,Green, K.J.,Tellam, J.,Kjer-Nielsen, L.,McCluskey, J.,Rossjohn, J.,Burrows, S.R. (登録日: 2005-09-05, 公開日: 2005-11-29, 最終更新日: 2017-10-11)

• 主引用文献: Tynan, F.E.,Elhassen, D.,Purcell, A.W.,Burrows, J.M.,Borg, N.A.,Miles, J.J.,Williamson, N.A.,Green, K.J.,Tellam, J.,Kjer-Nielsen, L.,McCluskey, J.,Rossjohn, J.,Burrows, S.R.; The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation; J.Exp.Med., 202:1249-1260, 2005; PubMed: 16275762; DOI: 10.1084/jem.20050864

実験手法

X-RAY DIFFRACTION (1.8 Å)