2ATP

Crystal structure of a CD8ab heterodimer

Summary for 2ATP

• Entry DOI: 10.2210/pdb2atp/pdb
• Related: 1BQH 1NEZ
• Descriptor: T-cell surface glycoprotein CD8 alpha chain, artifact linker, T-cell surface glycoprotein CD8 beta chain, ... (5 entities in total)
• Functional Keywords: cd8ab, cd8aa, mhc, immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01731 P10300
• Total number of polymer chains: 6
• Total formula weight: 60483.72

Authors

Chang, H.C.,Tan, K.,Ouyang, J.,Parisini, E.,Liu, J.H.,Le, Y.,Wang, X.,Reinherz, E.L.,Wang, J.H. (deposition date: 2005-08-25, release date: 2005-12-27, Last modification date: 2023-08-23)

• Primary citation: Chang, H.C.,Tan, K.,Ouyang, J.,Parisini, E.,Liu, J.H.,Le, Y.,Wang, X.,Reinherz, E.L.,Wang, J.H.; Structural and Mutational Analyses of a CD8alphabeta Heterodimer and Comparison with the CD8alphaalpha Homodimer.; Immunity, 23:661-671, 2005; PubMed: 16356863; DOI: 10.1016/j.immuni.2005.11.002

Experimental method

X-RAY DIFFRACTION (2.4 Å)