2ARM

Crystal Structure of the Complex of Phospholipase A2 with a natural compound atropine at 1.2 A resolution

2ARM の概要

• エントリーDOI: 10.2210/pdb2arm/pdb
• 関連するPDBエントリー: 1FVO 1Q7A
• 分子名称: Phospholipase A2 VRV-PL-VIIIa, (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: enzyme, complex, hydrolase
• 由来する生物種: Daboia russellii pulchella
• 細胞内の位置: Secreted: P59071
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14303.39

構造登録者

Singh, N.,Pal, A.,Jabeen, T.,Sharma, S.,Perbandt, M.,Betzel, C.,Singh, T.P. (登録日: 2005-08-20, 公開日: 2005-09-20, 最終更新日: 2011-07-13)

• 主引用文献: Singh, N.,Jabeen, T.,Pal, A.,Sharma, S.,Perbandt, M.,Betzel, C.,Singh, T.P.; Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding; Proteins, 64:89-100, 2006; PubMed: 16596639; DOI: 10.1002/prot.20970

実験手法

X-RAY DIFFRACTION (1.23 Å)