2AR8

The structure of tryptophan 7-halogenase (PrnA)suggests a mechanism for regioselective chlorination

2AR8 の概要

• エントリーDOI: 10.2210/pdb2ar8/pdb
• 関連するPDBエントリー: 2APG 2AQJ
• 分子名称: tryptophan halogenase PrnA, CHLORIDE ION, 7-CHLOROTRYPTOPHAN, ... (5 entities in total)
• 機能のキーワード: tryptophan 7-halogenase, flavin-dependent halogenase, helical bundle, sandwiched sheets, structural genomics, scottish structural proteomics facility, sspf, biosynthetic protein
• 由来する生物種: Pseudomonas fluorescens
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62205.76

構造登録者

Dong, C.,Flecks, S.,Unversucht, S.,Haupt, C.,Van Pee, K.H.,Naismith, J.H.,Scottish Structural Proteomics Facility (SSPF) (登録日: 2005-08-19, 公開日: 2005-10-04, 最終更新日: 2023-11-15)

• 主引用文献: Dong, C.,Flecks, S.,Unversucht, S.,Haupt, C.,van Pee, K.H.,Naismith, J.H.; Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.; Science, 309:2216-2219, 2005; PubMed: 16195462; DOI: 10.1126/science.1116510

実験手法

X-RAY DIFFRACTION (2.2 Å)