2AM2

sp protein ligand 2

Summary for 2AM2

Entry DOI	10.2210/pdb2am2/pdb
Related	2AM1
Descriptor	UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase, MurF protein, 2-CHLORO-N-(3-CYANO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-2-YL)-5-DIETHYLSULFAMOYL-BENZAMIDE (3 entities in total)
Functional Keywords	ligase
Biological source	Streptococcus pneumoniae
Total number of polymer chains	1
Total formula weight	51184.57
Authors	Longenecker, K.L.,Stamper, G.F.,Hajduk, P.J.,Fry, E.H.,Jakob, C.G.,Harlan, J.E.,Edalji, R.,Bartley, D.M.,Walter, K.A.,Solomon, L.R. (deposition date: 2005-08-08, release date: 2006-01-24, Last modification date: 2023-11-15)
Primary citation	Longenecker, K.L.,Stamper, G.F.,Hajduk, P.J.,Fry, E.H.,Jakob, C.G.,Harlan, J.E.,Edalji, R.,Bartley, D.M.,Walter, K.A.,Solomon, L.R.,Holzman, T.F.,Gu, Y.G.,Lerner, C.G.,Beutel, B.A.,Stoll, V.S. Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure Protein Sci., 14:3039-3047, 2005 Cited by PubMed: 16322581 DOI: 10.1110/ps.051604805 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation