2AM2

sp protein ligand 2

2AM2 の概要

関連するPDBエントリー2AM1
分子名称UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase, MurF protein, 2-CHLORO-N-(3-CYANO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-2-YL)-5-DIETHYLSULFAMOYL-BENZAMIDE (3 entities in total)
機能のキーワードligase
由来する生物種Streptococcus pneumoniae
ポリマー鎖数1
分子量合計51184.57
構造登録者
Longenecker, K.L.,Stamper, G.F.,Hajduk, P.J.,Fry, E.H.,Jakob, C.G.,Harlan, J.E.,Edalji, R.,Bartley, D.M.,Walter, K.A.,Solomon, L.R. (登録日: 2005-08-08, 公開日: 2006-01-24, 最終更新日: 2017-10-11)
主引用文献
Longenecker, K.L.,Stamper, G.F.,Hajduk, P.J.,Fry, E.H.,Jakob, C.G.,Harlan, J.E.,Edalji, R.,Bartley, D.M.,Walter, K.A.,Solomon, L.R.,Holzman, T.F.,Gu, Y.G.,Lerner, C.G.,Beutel, B.A.,Stoll, V.S.
Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure
Protein Sci., 14:3039-3047, 2005
PubMed: 16322581 (主引用文献が同じPDBエントリー)
DOI: 10.1110/ps.051604805
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.8 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.316425.1%7.4%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード

他の静止画像(非対称単位)

Molmil generated image of 2am2
回転なし
Molmil generated image of 2am2
x軸(左右方向)周りに90°回転
Molmil generated image of 2am2
y軸(上下方向)周りに90°回転