2AK5

beta PIX-SH3 complexed with a Cbl-b peptide

Summary for 2AK5

Entry DOI	10.2210/pdb2ak5/pdb
Descriptor	Rho guanine nucleotide exchange factor 7, 8-residue peptide from a signal transduction protein CBL-B (3 entities in total)
Functional Keywords	adaptor proteins, cin85, pix/cool, cbl, protein-protein interaction, endocytosis, endocytosis-exocytosis complex, endocytosis/exocytosis
Biological source	Rattus norvegicus (Norway rat) More
Cellular location	Cytoplasm: Q13191
Total number of polymer chains	3
Total formula weight	15589.09
Authors	Jozic, D.,Cardenes, N.,Deribe, Y.L.,Moncalian, G.,Hoeller, D.,Groemping, Y.,Dikic, I.,Rittinger, K.,Bravo, J. (deposition date: 2005-08-03, release date: 2005-10-11, Last modification date: 2023-08-23)
Primary citation	Jozic, D.,Cardenes, N.,Deribe, Y.L.,Moncalian, G.,Hoeller, D.,Groemping, Y.,Dikic, I.,Rittinger, K.,Bravo, J. Cbl promotes clustering of endocytic adaptor proteins. Nat.Struct.Mol.Biol., 12:972-979, 2005 Cited by PubMed: 16228008 DOI: 10.1038/nsmb1000 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation