2AFQ

1.9 angstrom crystal structure of wild-type human thrombin in the sodium free state

Summary for 2AFQ

• Entry DOI: 10.2210/pdb2afq/pdb
• Related: 1HAH 1PPB 1RD3
• Descriptor: Prothrombin, GLYCEROL, ... (4 entities in total)
• Functional Keywords: alpha-thrombin; coagulation; allostery; protease; coagulation factor ii, blood clotting, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734
• Total number of polymer chains: 4
• Total formula weight: 66954.68

Authors

Johnson, D.J.D.,Adams, T.E.,Huntington, J.A. (deposition date: 2005-07-26, release date: 2005-11-15, Last modification date: 2023-08-23)

• Primary citation: Johnson, D.J.D.,Adams, T.E.,Li, W.,Huntington, J.A.; Crystal structure of wild-type human thrombin in the Na+-free state; Biochem.J., 392:21-28, 2005; PubMed: 16201969; DOI: 10.1042/BJ20051217

Experimental method

X-RAY DIFFRACTION (1.93 Å)