2AE7

Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4GAL-T1) in Complex with Pentasaccharide

2AE7 の概要

• エントリーDOI: 10.2210/pdb2ae7/pdb
• 関連するPDBエントリー: 1O0R 1TVY 1TW1 1TW5 2AEC 2AES 2AGD 2AH9
• 分子名称: Beta-1,4-galactosyltransferase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, ... (9 entities in total)
• 機能のキーワード: beta1, 4-galactosyltransferase-i; pentasaccharide; closed conformation; mutant, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 103384.34

構造登録者

Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Ratner, D.M.,Seeberger, P.H.,Qasba, P.K. (登録日: 2005-07-21, 公開日: 2005-10-04, 最終更新日: 2023-08-23)

• 主引用文献: Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Ratner, D.M.,Seeberger, P.H.,Qasba, P.K.; Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety; J.Mol.Biol., 353:53-67, 2005; PubMed: 16157350; DOI: 10.1016/j.jmb.2005.07.050

実験手法

X-RAY DIFFRACTION (2 Å)