2AE2

TROPINONE REDUCTASE-II COMPLEXED WITH NADP+ AND PSEUDOTROPINE

Summary for 2AE2

Entry DOI	10.2210/pdb2ae2/pdb
Descriptor	PROTEIN (TROPINONE REDUCTASE-II), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PSEUDOTROPINE, ... (4 entities in total)
Functional Keywords	oxidoreductase, tropane alkaloid biosynthesis, reduction of tropinone to pseudotropine, short-chain dehydrogenase
Biological source	Datura stramonium (jimsonweed)
Total number of polymer chains	2
Total formula weight	58448.12
Authors	Yamashita, A.,Kato, H.,Wakatsuki, S.,Tomizaki, T.,Nakatsu, T.,Nakajima, K.,Hashimoto, T.,Yamada, Y.,Oda, J. (deposition date: 1999-01-26, release date: 1999-02-02, Last modification date: 2023-08-23)
Primary citation	Yamashita, A.,Kato, H.,Wakatsuki, S.,Tomizaki, T.,Nakatsu, T.,Nakajima, K.,Hashimoto, T.,Yamada, Y.,Oda, J. Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis. Biochemistry, 38:7630-7637, 1999 Cited by PubMed: 10387002 DOI: 10.1021/bi9825044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation