2AE2

TROPINONE REDUCTASE-II COMPLEXED WITH NADP+ AND PSEUDOTROPINE

2AE2 の概要

• エントリーDOI: 10.2210/pdb2ae2/pdb
• 分子名称: PROTEIN (TROPINONE REDUCTASE-II), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PSEUDOTROPINE, ... (4 entities in total)
• 機能のキーワード: oxidoreductase, tropane alkaloid biosynthesis, reduction of tropinone to pseudotropine, short-chain dehydrogenase
• 由来する生物種: Datura stramonium (jimsonweed)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58448.12

構造登録者

Yamashita, A.,Kato, H.,Wakatsuki, S.,Tomizaki, T.,Nakatsu, T.,Nakajima, K.,Hashimoto, T.,Yamada, Y.,Oda, J. (登録日: 1999-01-26, 公開日: 1999-02-02, 最終更新日: 2023-08-23)

• 主引用文献: Yamashita, A.,Kato, H.,Wakatsuki, S.,Tomizaki, T.,Nakatsu, T.,Nakajima, K.,Hashimoto, T.,Yamada, Y.,Oda, J.; Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis.; Biochemistry, 38:7630-7637, 1999; PubMed: 10387002; DOI: 10.1021/bi9825044

実験手法

X-RAY DIFFRACTION (1.9 Å)