2ACQ

AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE

2ACQ の概要

• エントリーDOI: 10.2210/pdb2acq/pdb
• 分子名称: ALDOSE REDUCTASE, 6-O-phosphono-alpha-D-glucopyranose, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36770.69

構造登録者

Harrison, D.H.,Bohren, K.M.,Gabbay, K.H.,Petsko, G.A.,Ringe, D. (登録日: 1994-04-15, 公開日: 1994-07-31, 最終更新日: 2024-02-14)

• 主引用文献: Harrison, D.H.,Bohren, K.M.,Ringe, D.,Petsko, G.A.,Gabbay, K.H.; An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate.; Biochemistry, 33:2011-2020, 1994; PubMed: 8117658; DOI: 10.1021/bi00174a006

実験手法

X-RAY DIFFRACTION (1.76 Å)