2AA7

Mineralocorticoid Receptor with Bound Deoxycorticosterone

Summary for 2AA7

• Entry DOI: 10.2210/pdb2aa7/pdb
• Related: 2AA2 2AA5 2AA6 2AAX 2AB2
• Descriptor: Mineralocorticoid receptor, SULFATE ION, DESOXYCORTICOSTERONE, ... (5 entities in total)
• Functional Keywords: mineralocorticoid receptor, mr, nuclear receptor, steroid receptor, deoxycorticosterone, hypertension, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P08235
• Total number of polymer chains: 1
• Total formula weight: 32221.23

Authors

Bledsoe, R.K.,Madauss, K.P.,Holt, J.A.,Apolito, C.J.,Lambert, M.H.,Pearce, K.H.,Stanley, T.B.,Stewart, E.L.,Trump, R.P.,Willson, T.M.,Williams, S.P. (deposition date: 2005-07-13, release date: 2005-07-26, Last modification date: 2024-02-14)

• Primary citation: Bledsoe, R.K.,Madauss, K.P.,Holt, J.A.,Apolito, C.J.,Lambert, M.H.,Pearce, K.H.,Stanley, T.B.,Stewart, E.L.,Trump, R.P.,Willson, T.M.,Williams, S.P.; A Ligand-mediated Hydrogen Bond Network Required for the Activation of the Mineralocorticoid Receptor; J.Biol.Chem., 280:31283-31293, 2005; PubMed: 15967794; DOI: 10.1074/jbc.M504098200

Experimental method

X-RAY DIFFRACTION (2.2 Å)