2A9U
Structure of the N-terminal domain of Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8)
Summary for 2A9U
| Entry DOI | 10.2210/pdb2a9u/pdb |
| Descriptor | Ubiquitin carboxyl-terminal hydrolase 8 (2 entities in total) |
| Functional Keywords | coil-coil, hydrolase, protease, sh3-binding, thiol protease, ubl conjugation pathway, structural genomics, structural genomics consortium, sgc |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P40818 |
| Total number of polymer chains | 2 |
| Total formula weight | 34052.29 |
| Authors | Walker, J.R.,Avvakumov, G.V.,Xue, S.,Newman, E.M.,Mackenzie, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, E.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2005-07-12, release date: 2005-08-16, Last modification date: 2011-07-13) |
| Primary citation | Avvakumov, G.V.,Walker, J.R.,Xue, S.,Finerty Jr., P.J.,Mackenzie, F.,Newman, E.M.,Dhe-Paganon, S. Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). J.Biol.Chem., 281:38061-38070, 2006 Cited by PubMed: 17035239DOI: 10.1074/jbc.M606704200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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