2A9U

Structure of the N-terminal domain of Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8)

2A9U の概要

• エントリーDOI: 10.2210/pdb2a9u/pdb
• 分子名称: Ubiquitin carboxyl-terminal hydrolase 8 (2 entities in total)
• 機能のキーワード: coil-coil, hydrolase, protease, sh3-binding, thiol protease, ubl conjugation pathway, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P40818
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34052.29

構造登録者

Walker, J.R.,Avvakumov, G.V.,Xue, S.,Newman, E.M.,Mackenzie, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, E.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (登録日: 2005-07-12, 公開日: 2005-08-16, 最終更新日: 2011-07-13)

• 主引用文献: Avvakumov, G.V.,Walker, J.R.,Xue, S.,Finerty Jr., P.J.,Mackenzie, F.,Newman, E.M.,Dhe-Paganon, S.; Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).; J.Biol.Chem., 281:38061-38070, 2006; PubMed: 17035239; DOI: 10.1074/jbc.M606704200

実験手法

X-RAY DIFFRACTION (2.1 Å)