2A6A

Crystal structure of Glycoprotein endopeptidase (tm0874) from THERMOTOGA MARITIMA at 2.50 A resolution

Summary for 2A6A

• Entry DOI: 10.2210/pdb2a6a/pdb
• Descriptor: hypothetical protein TM0874, UNKNOWN LIGAND (3 entities in total)
• Functional Keywords: tm0874, glycoprotein endopeptidase, structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi, hydrolase
• Biological source: Thermotoga maritima
• Total number of polymer chains: 2
• Total formula weight: 49246.32

Authors

Joint Center for Structural Genomics (JCSG) (deposition date: 2005-07-02, release date: 2005-07-19, Last modification date: 2024-11-13)

Primary citation

Xu, Q.,McMullan, D.,Jaroszewski, L.,Krishna, S.S.,Elsliger, M.A.,Yeh, A.P.,Abdubek, P.,Astakhova, T.,Axelrod, H.L.,Carlton, D.,Chiu, H.J.,Clayton, T.,Duan, L.,Feuerhelm, J.,Grant, J.,Han, G.W.,Jin, K.K.,Klock, H.E.,Knuth, M.W.,Miller, M.D.,Morse, A.T.,Nigoghossian, E.,Okach, L.,Oommachen, S.,Paulsen, J.,Reyes, R.,Rife, C.L.,van den Bedem, H.,Hodgson, K.O.,Wooley, J.,Deacon, A.M.,Godzik, A.,Lesley, S.A.,Wilson, I.A.
Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5 A resolution.
Acta Crystallogr.,Sect.F, 66:1230-1236, 2010

PubMed Abstract: YeaZ is involved in a protein network that is essential for bacteria. The crystal structure of YeaZ from Thermotoga maritima was determined to 2.5 Å resolution. Although this protein belongs to a family of ancient actin-like ATPases, it appears that it has lost the ability to bind ATP since it lacks some key structural features that are important for interaction with ATP. A conserved surface was identified, supporting its role in the formation of protein complexes.

PubMed: 20944216
DOI: 10.1107/S1744309109022192

Experimental method

X-RAY DIFFRACTION (2.5 Å)