2A2R

Crystal Structure of Glutathione Transferase Pi in complex with S-nitrosoglutathione

Summary for 2A2R

Entry DOI	10.2210/pdb2a2r/pdb
Related	1ZGN 2A2S 5GSS
Descriptor	Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-5-[1-(CARBOXYLATOMETHYLCARBAMOYL)-2-NITROSOSULFANYL-ETHYL]AMINO-5-OXO-PENTANOATE, ... (6 entities in total)
Functional Keywords	transferase, detoxification, nitric oxide carrier, s-nitrosoglutathione
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P09211
Total number of polymer chains	2
Total formula weight	47914.71
Authors	Parker, L.J.,Morton, C.J.,Adams, J.J.,Parker, M.W. (deposition date: 2005-06-23, release date: 2006-06-06, Last modification date: 2023-10-25)
Primary citation	Tellez-Sanz, R.,Cesareo, E.,Nuccetelli, M.,Aguilera, A.M.,Baron, C.,Parker, L.J.,Adams, J.J.,Morton, C.J.,Lo Bello, M.,Parker, M.W.,Garcia-Fuentes, L. Calorimetric and structural studies of the nitric oxide carrier S-nitrosoglutathione bound to human glutathione transferase P1-1 Protein Sci., 15:1093-1105, 2006 Cited by PubMed: 16597834 DOI: 10.1110/ps.052055206 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation