2A1R

Crystal structure of PARN nuclease domain

Summary for 2A1R

• Entry DOI: 10.2210/pdb2a1r/pdb
• Related: 2A1S
• Descriptor: 5'-R(*AP*AP*A)-3', Poly(A)-specific ribonuclease PARN (3 entities in total)
• Functional Keywords: parn, dedd, nuclease domain, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : O95453
• Total number of polymer chains: 4
• Total formula weight: 101119.59

Authors

Wu, M.,Song, H. (deposition date: 2005-06-21, release date: 2005-12-20, Last modification date: 2017-10-11)

• Primary citation: Wu, M.,Reuter, M.,Lilie, H.,Liu, Y.,Wahle, E.,Song, H.; Structural insight into poly(A) binding and catalytic mechanism of human PARN; Embo J., 24:4082-4093, 2005; PubMed: 16281054; DOI: 10.1038/sj.emboj.7600869

Experimental method

X-RAY DIFFRACTION (2.6 Å)