2EIZ
Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex
Summary for 2EIZ
Entry DOI | 10.2210/pdb2eiz/pdb |
Related | 2EKS |
Descriptor | ANTI-LYSOZYME ANTIBODY FV REGION, Lysozyme C, ... (4 entities in total) |
Functional Keywords | antibody, hydrolase, immune system-hydrolase complex, immune system/hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: 2EIZ |
Total number of polymer chains | 3 |
Total formula weight | 38446.90 |
Authors | Nakanishi, T.,Tsumoto, K.,Yokota, A.,Kondo, H.,Kumagai, I. (deposition date: 2007-03-14, release date: 2008-03-18, Last modification date: 2023-10-25) |
Primary citation | Nakanishi, T.,Tsumoto, K.,Yokota, A.,Kondo, H.,Kumagai, I. Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10 Protein Sci., 17:261-270, 2008 Cited by PubMed: 18227432DOI: 10.1110/ps.073156708 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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