2AM1

sp protein ligand 1

2AM1 の概要

• エントリーDOI: 10.2210/pdb2am1/pdb
• 関連するPDBエントリー: 2AM2
• 分子名称: UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase, MurF protein, 2,4-DICHLORO-N-(3-CYANO-4,5,6,7-TETRAHYDRO-BENZOTHIOPHEN-2YL)-5-(MORPHOLINE-4-SULFONYL)-BENZAMIDE, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: ligase
• 由来する生物種: Streptococcus pneumoniae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 51339.12

構造登録者

Longenecker, K.L.,Stamper, G.F.,Hajduk, P.J.,Fry, E.H.,Jakob, C.G.,Harlan, J.E.,Edalji, R.,Bartley, D.M.,Walter, K.A.,Solomon, L.R. (登録日: 2005-08-08, 公開日: 2006-01-24, 最終更新日: 2017-10-11)

• 主引用文献: Longenecker, K.L.,Stamper, G.F.,Hajduk, P.J.,Fry, E.H.,Jakob, C.G.,Harlan, J.E.,Edalji, R.,Bartley, D.M.,Walter, K.A.,Solomon, L.R.,Holzman, T.F.,Gu, Y.G.,Lerner, C.G.,Beutel, B.A.,Stoll, V.S.; Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure; Protein Sci., 14:3039-3047, 2005; PubMed: 16322581; DOI: 10.1110/ps.051604805

実験手法

X-RAY DIFFRACTION (2.5 Å)