295D

CRYSTAL AND SOLUTION STRUCTURES OF THE OLIGONUCLEOTIDE D(ATGCGCAT)2: A COMBINED X-RAY AND NMR STUDY

295D の概要

• エントリーDOI: 10.2210/pdb295d/pdb
• 分子名称: DNA (5'-D(*AP*TP*GP*CP*GP*CP*AP*T)-3') (2 entities in total)
• 機能のキーワード: a-dna, double helix, dna
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 2426.62

構造登録者

Clark, G.R.,Brown, D.G.,Sanderson, M.R.,Chwalinski, T.,Neidle, S.,Veal, J.M.,Jones, R.L.,Wilson, W.D.,Zon, G.,Garman, E.,Stuart, D.I. (登録日: 1991-05-28, 公開日: 1996-12-04, 最終更新日: 2024-02-14)

主引用文献

Clark, G.R.,Brown, D.G.,Sanderson, M.R.,Chwalinski, T.,Neidle, S.,Veal, J.M.,Jones, R.L.,Wilson, W.D.,Zon, G.,Garman, E.,Stuart, D.I.
Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study.
Nucleic Acids Res., 18:5521-5528, 1990

PubMed Abstract: A combined crystal-structure determination and NMR analysis of the octanucleotide d(ATGCGCAT)2 is reported. The X-ray analysis shows that the structure is A-form duplex in crystal state. The NMR study shows that in solution this sequence is B-type. The conformational results from each technique are presented in detail. The implications of these findings in terms of conformational flexibility and ligand binding are discussed.

PubMed: 2216724
DOI: 10.1093/nar/18.18.5521

実験手法

X-RAY DIFFRACTION (1.5 Å)