281D

CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)

Summary for 281D

• Entry DOI: 10.2210/pdb281d/pdb
• Descriptor: DNA (5'-D(*GP*GP*CP*AP*TP*GP*CP*C)-3') (2 entities in total)
• Functional Keywords: a-dna, double helix, dna
• Total number of polymer chains: 2
• Total formula weight: 4855.21

Authors

Nunn, C.M.,Neidle, S. (deposition date: 1996-08-23, release date: 1996-09-16, Last modification date: 2024-02-14)

Primary citation

Nunn, C.M.,Neidle, S.
Structure of the A-DNA octamer d(GGCATGCC).
Acta Crystallogr.,Sect.D, 53:269-273, 1997

PubMed Abstract: The crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex is non-linear with a helix axis curvature of 7 degrees and bending towards the DNA minor groove. In view of the biological importance of protein recognition of some A-DNA sequences the minor-groove geometry and helix-axis curvature for this structure is compared with all others of the type d(GGXATXCC).

PubMed: 15299929
DOI: 10.1107/S0907444996014795

Experimental method

X-RAY DIFFRACTION (2.38 Å)