281D

CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)

281D の概要

• エントリーDOI: 10.2210/pdb281d/pdb
• 分子名称: DNA (5'-D(*GP*GP*CP*AP*TP*GP*CP*C)-3') (2 entities in total)
• 機能のキーワード: a-dna, double helix, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 4855.21

構造登録者

Nunn, C.M.,Neidle, S. (登録日: 1996-08-23, 公開日: 1996-09-16, 最終更新日: 2024-02-14)

主引用文献

Nunn, C.M.,Neidle, S.
Structure of the A-DNA octamer d(GGCATGCC).
Acta Crystallogr.,Sect.D, 53:269-273, 1997

PubMed Abstract: The crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex is non-linear with a helix axis curvature of 7 degrees and bending towards the DNA minor groove. In view of the biological importance of protein recognition of some A-DNA sequences the minor-groove geometry and helix-axis curvature for this structure is compared with all others of the type d(GGXATXCC).

PubMed: 15299929
DOI: 10.1107/S0907444996014795

実験手法

X-RAY DIFFRACTION (2.38 Å)