263D

ISOHELICITY AND PHASING IN DRUG-DNA SEQUENCE RECOGNITION: CRYSTAL STRUCTURE OF A TRIS(BENZIMIDAZOLE)-OLIGONUCLEOTIDE COMPLEX

Summary for 263D

• Entry DOI: 10.2210/pdb263d/pdb
• Descriptor: DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3'), 2''-(4-METHOXYPHENYL)-5-(3-AMINO-1-PYRROLIDINYL)-2,5',2',5''-TRI-BENZIMIDAZOLE (3 entities in total)
• Functional Keywords: b-dna, double helix, complexed with drug, dna
• Total number of polymer chains: 2
• Total formula weight: 7866.43

Authors

Clark, G.R.,Gray, E.J.,Neidle, S.,Li, Y.-H.,Leupin, W. (deposition date: 1996-09-27, release date: 1996-10-15, Last modification date: 2024-04-03)

• Primary citation: Clark, G.R.,Gray, E.J.,Neidle, S.,Li, Y.H.,Leupin, W.; Isohelicity and phasing in drug--DNA sequence recognition: crystal structure of a tris(benzimidazole)--oligonucleotide complex.; Biochemistry, 35:13745-13752, 1996; PubMed: 8901516; DOI: 10.1021/bi960421m

Experimental method

X-RAY DIFFRACTION (2.2 Å)