263D

ISOHELICITY AND PHASING IN DRUG-DNA SEQUENCE RECOGNITION: CRYSTAL STRUCTURE OF A TRIS(BENZIMIDAZOLE)-OLIGONUCLEOTIDE COMPLEX

Summary for 263D

DescriptorDNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3'), 2''-(4-METHOXYPHENYL)-5-(3-AMINO-1-PYRROLIDINYL)-2,5',2',5''-TRI-BENZIMIDAZOLE (3 entities in total)
Functional Keywordsb-dna, double helix, complexed with drug, dna
Total number of polymer chains2
Total molecular weight7866.43
Authors
Clark, G.R.,Gray, E.J.,Neidle, S.,Li, Y.-H.,Leupin, W. (deposition date: 1996-09-27, release date: 1996-10-15, Last modification date: 2011-07-13)
Primary citation
Clark, G.R.,Gray, E.J.,Neidle, S.,Li, Y.H.,Leupin, W.
Isohelicity and phasing in drug--DNA sequence recognition: crystal structure of a tris(benzimidazole)--oligonucleotide complex.
Biochemistry, 35:13745-13752, 1996
PubMed: 8901516 (PDB entries with the same primary citation)
DOI: 10.1021/bi960421m
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

ClashscoreRSRZ outliers170MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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