24VS

Cryo-EM structure of the human KCNQ2/KCNQ3 heterotetramer (1:3 stoichiometry) in apo state (M2333 apo, with symmetry expansion)

24VS の概要

• エントリーDOI: 10.2210/pdb24vs/pdb
• EMDBエントリー: 69850
• 分子名称: Potassium voltage-gated channel subfamily KQT member 3, Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 2, (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate, ... (4 entities in total)
• 機能のキーワード: potassium channels, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 299515.17

構造登録者

Wang, Y.F.,Yang, H.,Qu, Y.N.,Shen, H.Z. (登録日: 2026-03-22, 公開日: 2026-08-12)

• 主引用文献: Wang, Y.,Yang, H.,Qu, Y.,Li, J.,Li, X.,Hou, W.,Wu, K.,Xie, G.,Wang, X.,Ye, Y.,Yang, H.,Shen, H.; Structural basis for heteromeric assembly and subthreshold activation of human M-channel; Vita, 2026; DOI: 10.15302/vita.2026.05.0032

実験手法

ELECTRON MICROSCOPY (3.51 Å)